• Pragati Abhyankar
• Pooja Jamdar
• Aishwarya Pradhan

Lactic acid bacteria are widely distributed in the nature. They can be isolated from soil, water, plants, silage, from the intestinal tract of animals and humans and fermented food products. Lactic Acid Bacteria (LAB) are characterized as Gram positive, usually non-motile, non-sporulating bacteria that produce lactic acid as a major or sole product of fermentative metabolism. Lactic acid bacteria are among the best studied microorganisms for human health advantageous effects and fermentation. Significant novel developments have been made on lactic acid bacteria in the area of multidrug resistance, bacteriocins, osmoregulation, autolysins and bacteriophages. Different lactobacilli, bifidobacteria, or probiotic mixtures have been shown to alleviate digestive diseases in experimental animals and in inflammatory bowel diseases in humans. Antimicrobial activities of LAB have been demonstrated in various species. Some LAB can prevent the adherence, establishment and invasion or toxin production of intestinal or vaginal pathogens. Health benefits currently being investigated in favour of probiotic microorganisms include their role in alleviating chronic intestinal inflammatory diseases; prevention and treatment of pathogen induced diarrhoea; urogenital infections and atopic diseases. The present study investigates the inhibitory activity of LAB against the pathogens of urinary tract infection. The LAB used in this study were isolated from plant sources along with use of curd to isolate LAB. The LAB were isolated and characterised and their inhibitory activity was checked against the pathogens of urinary tract infection. LAB showed a greater range of inhibitory activity than observed for antibiotics commonly used against the pathogens.

Lactic Acid Bacteria, Urinary Tract Infections, Pathogens, Bacteriocins, Inhibition

"Isolation and characterisation of Lactic Acid bacteria and their role in inhibiting the pathogens of Urinary Tract Infections", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 8, page no.c320-c328, August-2021, Available :http://www.jetir.org/papers/JETIR2108291.pdf

"Isolation and characterisation of Lactic Acid bacteria and their role in inhibiting the pathogens of Urinary Tract Infections", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 8, page no. ppc320-c328, August-2021, Available at : http://www.jetir.org/papers/JETIR2108291.pdf