• M.Ramya Teja
• Sk. Sufiya
• T.Rama Krishna
• Ch, Madhav Reddy
• Sk. Shaheena

The aim of the present research study was to prepare and evaluate the Glibenclamide transdermal patches in order to enhance the permeation of the drug and to study the effectiveness of the two polymers used and their physiochemical properties to know about the invitro drug profile. The main polymers used here are Chitosan, HPMC and Ethyl cellulose. Employing these polymers shows no interaction with the drug. Glibenclamide transdermal patches was prepared by Solvent Casting technique. Thus, the prepared formulation was evaluated under the parameters like thickness, weight uniformity, folding endurance, moisture content, moisture loss, drug content, drug profile, invitro drug release performed by using Franz diffusion cells. Drug delivery through the skin gives a systemic effect and does not alter the plasma level concentrations of the drug. Thus, Glibenclamide transdermal patch is used as a control drug delivery system and administrable frequency of the drug is minimized .

HPMC, EC, Glibenclamide, Transdermal Patches

"FORMULATION AND EVALUATION OF GLIBENCLAMIDE TRANSDERMAL PATCHES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 8, page no.e589-e602, August-2021, Available :http://www.jetir.org/papers/JETIR2108559.pdf

"FORMULATION AND EVALUATION OF GLIBENCLAMIDE TRANSDERMAL PATCHES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 8, page no. ppe589-e602, August-2021, Available at : http://www.jetir.org/papers/JETIR2108559.pdf