• Athulya Peter
• Baskar lakshmanan
• Cholaraja kamatchi

The emergence of drug-resistant microbes left us with a great need for new antimicrobial agents. Aminopyrimidines, with their wide range of biological activities, are good candidates in this respect. The derivatives of the title scaffold had proven to possess great potential, inhibiting and cidal activity of microbes even at concentrations below 1 μg ml−1. The substitution pattern of these aminopyrimidines often includes hydroxy groups, halogens or other heteroaromic rings, In this article, we aim to report the molecular docking and in-vitro antimicrobial activity of our novel derivatives AD (1-6). Among all six novel derivatives, two of them AD3 & AD4 were showing significant antimicrobial activity against both the gram positive and gram negative bacteria.

2-Aminopyrimidine derivatives, Molecular docking, Antimicrobial acti

"Molecular docking and in-vitro antimicrobial activity of some novel aminopyrimidine derivatives", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 9, page no.b35-b45, September-2021, Available :http://www.jetir.org/papers/JETIR2109105.pdf

"Molecular docking and in-vitro antimicrobial activity of some novel aminopyrimidine derivatives", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 9, page no. ppb35-b45, September-2021, Available at : http://www.jetir.org/papers/JETIR2109105.pdf