• DR.M.ABISHEK CHAKKARAVARTHI
• DR.A.JOSEPHINE
• DR.VINDU SRIVASTAVA

Viral infections are associated with thrombocytopenia due to variety of causes. It is usually caused by enhanced platelet clearance destruction, while in the later parts of SARS-Cov2, hypo-proliferates thrombocytopenia is observed. Platelets can be activated by viral antigen-antibody complexes. In 2019 and 2021 the severe acute respiratory syndrome coronovirus2 (SARS-Cov-2) has swept all-over the world. Eighty per cent of the patients infected by SARS-Cov-2 may be a symptomatic direct viral-platelet interaction and activation; formation of platelet to leukocyte aggregates; FcR- Mediated infraction with immune complexes. Platelets are important in maintaining vascular homeostasis and endothelial integrity in end organs. During Covid-19 infection, platelets are stimulated activated and recreated at the site of infection. They activate inflammatory process and are responsible complications of coagulopathy. The aim of this review is to present the platelets fraction contribution in clinical practice. Here we will provide a comprehensive review of the history and the current state of the artificial platelet approaches along with discussing the translational challenges and opportunities

Platelets, SARS-Cov2, Thrombocytopenia, Coagulopathy, Megakaryocytes, Molecules, Phagocytosis, Neutrophils, Cytokine

"SYSTEMATIC REVIEW ON PLATELET AND SARS Cov2 INFECTION", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 9, page no.c295-c298, September-2021, Available :http://www.jetir.org/papers/JETIR2109238.pdf

"SYSTEMATIC REVIEW ON PLATELET AND SARS Cov2 INFECTION", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 9, page no. ppc295-c298, September-2021, Available at : http://www.jetir.org/papers/JETIR2109238.pdf