• Mr. Swapnil R. Patil
• Vishakha R. Janjale
• Akshada S.Chaudhari

Abstract: West Nile virus (WNV) is a single-stranded RNA virus that causes West Nile fever. It is a member of the family Flaviviridae, from the genus Flavivirus, which also contains the Zika virus, dengue virus, and yellow fever virus. The virus is primarily transmitted by mosquitoes, mostly species of Culex. West Nile virus, a mosquito-borne infection that can cause serious illness, and in some cases, death, was first found in New York State in 1999. While the chances of anyone becoming ill are small, persons over age 50 are at higher risk for serious illness. West Nile virus (WNV) is a Japanese encephalitis antigenic complex of Flaviviridae family. It is transmitted by the bite of infected mosquitoes. The virus is maintained in a mosquito–bird–mosquito transmission cycle. Mild signs and symptoms of a West Nile virus infection generally go away on their own. But severe signs and symptoms such as a severe headache, fever, disorientation or sudden weakness need immediate attention. Exposure to mosquitoes where West Nile virus exists increases your risk of getting infected. There is no specific treatment for West Nile virus infection. Mild illness does not require therapy other than medication to reduce fever and pain. When West Nile infects the brain, intensive supportive therapy is needed. There are no vaccines to prevent or medications to treat WNV in people. Fortunately, most people infected with WNV do not feel sick. About 1 in 5 people who are infected develop a fever and other symptoms. About 1 out of 150 infected people develop a serious, sometimes fatal, illness. The information about prevalence of WNV among animal population in India is scanty. This review updates the most recent investigations in different aspects of WNV life cycle: molecular virology, transmission, host range, epidemiology, pathogenesis, diagnosis, , and highlights some aspects that certainly require further research.

Keywords: West Nile Virus, Mosquitoes, Epidemiology, Diagnosis, Vaccines.

"“Review On West Nile Virus Disease: Its Outbreak And Current Status”", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 9, page no.d200-d212, September-2021, Available :http://www.jetir.org/papers/JETIR2109320.pdf

"“Review On West Nile Virus Disease: Its Outbreak And Current Status”", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 9, page no. ppd200-d212, September-2021, Available at : http://www.jetir.org/papers/JETIR2109320.pdf