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October-2021
eISSN: 2349-5162
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Journal of Emerging Technologies and Innovative Research ( An International Scholarly Open Access Journal, Peer-reviewed, Refereed Journal )
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UGC Approved Journal no 63975(19)
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UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975
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Published Paper ID:
JETIR2110045
Registration ID:
315406
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Title
CHARACTERIZATION & IMMUNO- MODULATORY ACTIVITY OF CAPSICUM ANNUUM L. VAR. GROSSUM SENDT. BY USING LABORATORY ANIMALS
Abstract
The present study was aimed to investigate Immuno-modulatory activity of Capsicum annuum L. var. grossum Sendt.The assessment of immuno-modulatory activity was carried out by using Neutrophil Adhesion Test (In-Vivo Method) & T-Cell Population (In-Vitro Method). Oral administration of extract of Capsicum annuum L. var. grossum Sendt. Significantly showed Immuno-modulatory activity increases percentage neutrophil adhesion, increases lymphocytes & No. of rosette count when result compared with control group. Separation was done by Thin Layer Chromatography (TLC) & then isolation was done by column chromatography technique & confirmed by spectroscopic techniques. In conclusion, ethanolic & aqueous extract of Capsicum annuum L. var. grossum Sendt. showed presence of flavonoids, phenolic compound & vitamin C. as well as alkaloids, glycosides. But aqueous extract showed maximum immunomodulatory activity by both In-vivo & In-vitro methods. So, further first performed Thin Layer chromatography & then flavonoid quercetin was isolated from aqueous extract of Capsicum annuum L. var. grossum Sendt. by column chromatography technique. Its presence was confirmed by spectroscopic analysis (UV, IR, NMR & MS) techniques.
Key Words
Immuno-Modulatory, Capsicum annuum L. var. grossum Sendt, Neutrophil Adhesion Test, T-Cell Population, Immunostimulant’s.
Cite This Article
"CHARACTERIZATION & IMMUNO- MODULATORY ACTIVITY OF CAPSICUM ANNUUM L. VAR. GROSSUM SENDT. BY USING LABORATORY ANIMALS ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 10, page no.a337-a356, October-2021, Available :http://www.jetir.org/papers/JETIR2110045.pdf
ISSN
2349-5162 | Impact Factor 7.95 Calculate by Google Scholar
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Cite This Article
"CHARACTERIZATION & IMMUNO- MODULATORY ACTIVITY OF CAPSICUM ANNUUM L. VAR. GROSSUM SENDT. BY USING LABORATORY ANIMALS ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 10, page no. ppa337-a356, October-2021, Available at : http://www.jetir.org/papers/JETIR2110045.pdf
Publication Details
Published Paper ID: JETIR2110045
Registration ID: 315406
Published In: Volume 8 | Issue 10 | Year October-2021
Page No: a337-a356
Country: -, -, India .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication
Published Paper URL :: https://www.jetir.org/view?paper=JETIR2110045
Published Paper PDF: https://www.jetir.org/papers/JETIR2110045
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