UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 8 Issue 10
October-2021
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2110113


Registration ID:
315769

Page Number

b113-b122

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Title

Combined effect of aqueous extracts of zingiber officinale and curcuma longa on male reproductive hormones of male wistar rats

Abstract

Objective: This study was carried out to investigate on the combined effect of aqueous extracts of zingiber officinale (Z. officinale) and Curcuma longa (C. longa) on male reproductive hormones of male wistar rats. Methodology: Thirty-five (35) male wistar rats weighing 130-180g were procured and acclimatized for two weeks, after which they were divided into seven (7) groups of five (5) rats each, and were housed in cages. The groups were designated as groups A, B, C, D, E, F and G. Group A served as control group and received only distilled water; while Groups B and C received 200mg/kg and 400mg/kg of Z. officinale extract respectively, Groups D and E received 200 and 400mg/kg of C. longa extract respectively, Group F received 100mg/kg of Z. officinale + 100mg/kg C. longa extracts, and Group G received 200mg/kg of Z. officinale + 200mg/kg of C. longa extracts for 21 days through oral route with the aid of oral gastric tube. On the 22nd day, the animals were sacrificed by chloroform inhalation, and blood samples were obtained through cardiac puncture for hormonal assays. Data obtained were analyzed using SPSS version 25 and (P<0.05) was considered significant. Result: The hormonal levels of testosterone, luteinizing hormone and follicle stimulating hormone were significantly (P<0.05) increased in groups C, E and G which received 400mg/kg of the extracts when compared with the control group. However, there was no significant difference on the levels of testosterone, LH and FSH levels for groups B, D and F which received 200mg/kg of the extracts compared with the control group. Conclusion: Combined extracts of Z. officinale and C. longa are more potent when taken together for the prevention and treatment of male infertility.

Key Words

Zingiber officinale, Curcuma longa, testosterone, luteinizing hormone (LH) follicle, stimulating hormone (FSH).

Cite This Article

" Combined effect of aqueous extracts of zingiber officinale and curcuma longa on male reproductive hormones of male wistar rats", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 10, page no.b113-b122, October-2021, Available :http://www.jetir.org/papers/JETIR2110113.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

" Combined effect of aqueous extracts of zingiber officinale and curcuma longa on male reproductive hormones of male wistar rats", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 10, page no. ppb113-b122, October-2021, Available at : http://www.jetir.org/papers/JETIR2110113.pdf

Publication Details

Published Paper ID: JETIR2110113
Registration ID: 315769
Published In: Volume 8 | Issue 10 | Year October-2021
DOI (Digital Object Identifier):
Page No: b113-b122
Country: Nnewi Campus, Anambra State, Nigeria .
Area: Medical Science
ISSN Number: 2349-5162
Publisher: IJ Publication


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