• Arun M. Mahale
• Amol Harsulkar
• Avinash V. Dhoble

ABSTRACT The disagreeable taste of drugs causes difficulties in swallowing causes patients to avoid their medication. Many antibiotics have an extremely bitter oral administration of drugs with obnoxious and bitter tastes with acceptable level of palatability is a challenge in pediatric and geriatric formulation. Suspension helps to pharmacy and medicine by supplying Insoluble and unpalatable substance in the form of acceptable dosage form. Earlier many methods for taste masking have been used which include use of ion exchange resin, complexation and coating of drugs. So, objective behind this study is to formulation and evaluation of taste masked ofloxacin oral suspension. Ofloxacin is a broad spectrum antibiotic for the treatment of Chlamydial and non-gonococci infections. In present work an attempt has been made to mask the taste of ofloxacin by using Indion Ion Exchange resign and suspension is prepared in different six batches. All the batches were evaluated for various evaluation parameters like Drug Content, pH, Bitterness, Viscocity, Sedimentation, Rate and Time and Percentage Drug release. All the batches were shown satisfactory results. The study results showed that formulation batch F5 meet the requirements official standards. Finally it could be conclude that the oral palatable taste masked suspension can be prepared by using Indion Ion Exchange resign for pediatrics and geriatrics patients.

Suspension, Ion-Exchange Resin, Ofloxacin, Indion 204, Indion 234

"FORMULATION AND EVALUATION OF TASTE MASKED OFLOXACIN ORAL SUSPENSION", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 10, page no.b149-b156, October-2021, Available :http://www.jetir.org/papers/JETIR2110117.pdf

"FORMULATION AND EVALUATION OF TASTE MASKED OFLOXACIN ORAL SUSPENSION", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 10, page no. ppb149-b156, October-2021, Available at : http://www.jetir.org/papers/JETIR2110117.pdf