• Pranjul Shrivastava
• Khushboo Gupta
• S.R Rashmi

Chemotherapy induced nausea and vomiting (CINV) is a grieve symptom in children receiving cancer treatment that imparts their quality of life. More than 40 per cent of children receiving cancer treatment reported nausea and vomiting caused by chemotherapy even when antiemetic medications were used. With the recent approach in antiemetic drugs the current treatments of CINV have become highly effectual in reducing the adverse effects. In addition, there are emerging patient derived risk factors associated with CINV which should be decoded. Objective- The aim of this review is to evaluate the current practice in antiemetic medicaments for paeditrics undergoing CINV. Conclusion- The review highlighted a lack of conscientiously developed CINV pharmacological treatment for paeditrics patients. Contemporary studies have shown espousal of “triple therapy” regimen of antiemetic prophylaxis (5-HT3 antagonist, dexamethasone and neurokinin-1) as a foundation for prevention of CINV in paeditrics.

Nausea, Vomiting, Antiemetics, CINV, Chemotherapy, Paeditrics

"A review on antiemetic drugs used for chemotherapy induced nausea and vomiting in paediatric patients", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 11, page no.c670-c675, November-2021, Available :http://www.jetir.org/papers/JETIR2111289.pdf

"A review on antiemetic drugs used for chemotherapy induced nausea and vomiting in paediatric patients", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 11, page no. ppc670-c675, November-2021, Available at : http://www.jetir.org/papers/JETIR2111289.pdf