• Omme Sayfun
• Mst. Rashida Khatun
• Dr. Md. Manjur Hossain

The diabetic retinopathy is a neurovascular complication of diabetes mellitus and it is the leading cause of vision loss among working adults worldwide. Homocysteine is a sulfur containing amino acid derived from the methionine metabolism. Homocysteine is an emerging risk factor for cardiovascular and nondiabetic ocular vaso-occlusive diseases. Studies indicate that mild elevations of homocysteine in plasma are associated with an increased risk for occlusive vascular disease, thrombosis, and stroke. The purpose of this study was to evaluate the relationship between plasma total homocysteine concentration and diabetic retinopathy. A descriptive hospital based cross-sectional study was conducted at Mymensingh Medical college Hospital. Blood samples were collected from the study subjects to estimate serum homocysteine (Hcy), fasting blood sugar (FBS), and blood pressure were measured and data were compiled for analysis. Homocysteine level was found to be significantly higher in cases (19.17 ± 6.13 μmol/L) with Diabetic retinopathy patients compared to controls (11.75 ± 4.43 μmol/L) Hyperhomocysteinaemia is associated with diabetic retinopathy and may play a role as a risk factor for the development of diabetic retinopathy.

Hyperhomocysteinaemia; Serum Homocysteine; Diabetic

"Serum Homocysteine Level Among Type-2 Diabetic Patients with and without Diabetic Retinopathy", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 12, page no.d239-d247, December-2021, Available :http://www.jetir.org/papers/JETIR2112330.pdf

"Serum Homocysteine Level Among Type-2 Diabetic Patients with and without Diabetic Retinopathy", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 12, page no. ppd239-d247, December-2021, Available at : http://www.jetir.org/papers/JETIR2112330.pdf