• G. Bhavani Devi
• K S Ramya
• P. Josthna
• C.V.Naidu

Solanum nigrum is one of the Indian medicinal plants which belong to the family Solanaceae. The whole plant is reported to have many biological activities such as antiseptic, antidysentric, antidiuretic and also has gastric ulcerogenic activity. The present study was carried out to investigate possible qualitative and quantitative phytochemical screening, antioxidant and antibacterial activity of various extracts of S. nigrum leaf, stem and root. Qualitative phytochemical screening of the extracts (ethanol, methanol, petroleum ether and aqueous) was performed to detect the presence of different kinds of phytoconstituents. Phytochemical screening exposed the presence of alkaloids, terpenoids, flavonoids, phenols, saponins, cardiac glycosides, resins and anthroquinones amid all the tested samples. Quantitative screening showed that the aqueous extract of leaf has high amount of total phenolics (28.03 ± 1.20 mg/gm), ethanolic extract of leaf showed highest amount of total flavonoids (48.19 ± 0.07mg/gm) and aqueous extract of stem expressed highest percentage of antioxidant activity (56.70 ± 0.10 µg/gm). The antibacterial activity was scrutinized against gram positive and gram negative bacteria by using disc diffusion method. All the extracts showed high activity against all the strains. Maximum zone of inhibition is shown by ethanolic stem extract against Klebsiella pneumonia. Among various types of extracts tested petroleum ether and aqueous extract showed lowest minimum inhibitory concentration values (4.25 µg/ml) against E. coli. A lowest MIC value was recorded against Bacillus subtilis.

Solanum nigrum, solvent extracts, phytochemical analysis, total phenols, total flavonoids, antioxidant, antibacterial activity.

"Evaluation of phytochemical screening, total phenols, flavonoids, antioxidant and antibacterial activity of various plant parts of extracts of Solanum nigrum L.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 12, page no.e426-e438, December-2021, Available :http://www.jetir.org/papers/JETIR2112455.pdf

"Evaluation of phytochemical screening, total phenols, flavonoids, antioxidant and antibacterial activity of various plant parts of extracts of Solanum nigrum L.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 12, page no. ppe426-e438, December-2021, Available at : http://www.jetir.org/papers/JETIR2112455.pdf