• Khudsia Hussain
• D.Srinivasa Rao

Actinobacteria of marine origin are considered to be a good and efficient source of secondary metabolites having been developed for clinical use. Streptomyces is the largest genus of actinobacteria belonging to the family Streptomycetaceae. It is gram positive with enhanced GC content. Streptomyces is synonymous with the production of numerous naturally originated antibiotics having a multitude of uses. It has been established that the coastal wetland inhabiting actinobacteria possess broad spectrum antimicrobial activities. This forms the basis that they are able to generate newer bioactive substances. In the present investigation the antimicrobial activities of marine actinobacteria- Streptomyces sp., namely, Streptomyces alboniger, Streptomyces coelicolor and Streptomyces griseus that were isolated from the Machilipatnam coast area was studied against the clinical bacteria consisting of Gram positive Staphylococcus aureus, Streptococcus faecalis and Gram negative Proteus vulgaris and Salmonella typhi. .

Actinobacteria, Streptomyces, antimicrobial, bioactive, metaboloites.

"Antimicrobial Activities of Marine Actinobacteria Streptomyces sp. isolated from Machilipatnam coast area ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.8, Issue 12, page no.e509-e517, December-2021, Available :http://www.jetir.org/papers/JETIR2112462.pdf

"Antimicrobial Activities of Marine Actinobacteria Streptomyces sp. isolated from Machilipatnam coast area ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.8, Issue 12, page no. ppe509-e517, December-2021, Available at : http://www.jetir.org/papers/JETIR2112462.pdf