• Dr. Meenal Gupta

Abstract: Cancer is a crucial disease amongst others that cause death of millions people in worldwide. Due to abnormal growth of normal cells internally and underwent by repeating division of cells with growing unwanted tissue in translation and transcription processes cause cancer. According to GLOBOCAN 2018 database, 18.1 million cases have arisen and 9.6 million death in 2018. Every 5th man and 6th women cause of cancer in worldwide. It is expected to rise 21 million by 2030, both developing and developed countries are unlikely underwent as crab’s paw hold on this deadly disease. Its incidence is expected to rise by about 70% over the next two decades.It is life-threatening disease and produces various side effects in the different parts of the body due to toxicity of chemotherapeutic processes (surgery and radiations) therefore increasing demand of people, researcher and scientists have been keeping its attention towards natural product originated from fauna and flora that use in the treatment of cancer and enhance immunity from long time period. Various bioactive phyto-constituents isolated and identified for its treatment which based on their mechanism of actions and design synthetic derivatives to cure and control this disease. Natural anticancer drugs have been discovered as therapeutic agents and composed of diverse functional groups contained various skeleton like indole, diketo conjugated with aromatic rings, triterpenes, flavonoids, saponins, lycopenes, carotenoids, quinones and lactones etc from traditional medicinal plants. They are natural antioxidants and prevent abnormal growth of cells in the body and stop the faster breakdown the cells. Hence on the basis of literature study, this review compiled all information have been made from naturally originated drugs and challenges based on cancer that will be more pronounced and effective throughout the disease.

Index Terms- Cancer, Cause and Mechanism, Anticancer Natural Products.

"POTENTIAL ANTICANCER PHYTOCONSTITUENTS FROM NATURAL PRODUCTS-A REVIEW", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 1, page no.a349-a358, January-2022, Available :http://www.jetir.org/papers/JETIR2201046.pdf

"POTENTIAL ANTICANCER PHYTOCONSTITUENTS FROM NATURAL PRODUCTS-A REVIEW", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 1, page no. ppa349-a358, January-2022, Available at : http://www.jetir.org/papers/JETIR2201046.pdf