• Armin Wijaya

Background: Postpartum haemorrhage is generally defined as blood loss exceeding 500 milliliters after vaginal delivery and 1000 ml after cesarean section. The most commonly used drugs in the management of PPH are uterotonic agents including misoprostol. Methods: This study is a quasi-experimental prospective study with a clinical trial design that compares the efficacy of misoprostol 400 mcg given preoperatively and postoperatively in the September 2020 period until the number of samples is fulfilled as many as 54 subjects. Results: There were statistically significant differences in the amount of blood from gauze, the amount of blood from suction, intra-operative bleeding, post-operative bleeding, and total bleeding (p<0.05) but there was no significant difference in the amount of gauze used.(p> 0.05) There was no statistically significant difference in the secondary outcomes (fever, chills, and nausea and vomiting) which was statistically significant in the two groups (p=1.00) There was a difference in the mean pre-operative and post-operative hemoglobin and hematocrit levels between the two treatment groups (p<0.001 and p=0.002). Conclusion: There is a difference in the mean difference between hemoglobin and hematocrit between pre-operative and post-operative hemoglobin and hematocrit in the two treatment groups.

misoprostol, sublingual, preoperative, postoperative, caesarean section

"COMPARISON OF THE EFFECTS OF PREOPERATIVE AND POSTOPERATIVE SUBLINGUAL SUBLINGUAL MISOPROSTOL IN THE TREATMENT OF POSTARTUM BLOODING PREVENTION", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 1, page no.c735-c742, January-2022, Available :http://www.jetir.org/papers/JETIR2201294.pdf

"COMPARISON OF THE EFFECTS OF PREOPERATIVE AND POSTOPERATIVE SUBLINGUAL SUBLINGUAL MISOPROSTOL IN THE TREATMENT OF POSTARTUM BLOODING PREVENTION", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 1, page no. ppc735-c742, January-2022, Available at : http://www.jetir.org/papers/JETIR2201294.pdf