• Dr.Raghu Nataraj
• J Bindu

Fibrinolysis is a process of degradation of the fibrin clots by Plasmin. Plasmin, a proteolytic enzyme produced from plasminogen (a zymogen) conversion with the influence of fibrinolytic agents like Tissue Plasminogen Activator (tPA). The current review is focused on shedding light on different such fibrinolytic agents, mechanism of action and their therapeutic applications. Different fibrinolytic agents such as Tissue Plasminogen Activator, Streptokinase and Urokinase etc. have been used in Fibrinolytic therapy aiding to minimize the size of clots formed in the arteries of brain, heart, lungs and veins of leg and preventing serious cardiovascular complications. The current review tries to shed light on the mechanism of fibrinolysis, its complications and its related discussion w.r.t several fibrinolytic agents in current use.

Fibrinogen, Fibrin, Plasminogen, Plasmin, Fibrinolytic agent & Fibrinolysis

"FIBRINOLYSIS & FIBRINOLYTIC AGENTS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 1, page no.e644-e648, January-2022, Available :http://www.jetir.org/papers/JETIR2201489.pdf

"FIBRINOLYSIS & FIBRINOLYTIC AGENTS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 1, page no. ppe644-e648, January-2022, Available at : http://www.jetir.org/papers/JETIR2201489.pdf