• SP Malarkannan
• P Dharumarajan
• Markandeyan Devaprasad
• MK Hariyohesh

Aims and objectives To do insilico screening of phytochemicals present in herbal preparation M V Kashayam using docking method against antiretroviral drug targets used against HIV (Human immunodeficiency virus) Method Phytochemical ligands of the herbs were docked against HIV Reverse transcriptase structures 6KDJ and 1S1X and Protease structure 3WJS downloaded from the RCSB-PDB site using Auto-Dock Vina PyRX screening software and the docking scores were compared against docking scores of antiretroviral drug ligands lamivudine, Nevirapine and Indanavir. Results and conclusion Amentoflavone, Cordifolide, Neoandrographolide, Queretaroic acid, Amritoside showed good docking scores in the active site of 6KDJ. Tinosporide, Piperlonguminine, Serratin, Tricostachine, Tinosporaside showed good docking scores in the active site of 1S1X. Palmatoside, Cordifolide, Neoandrographolide, Tinasporaside, Amritoside showed good docking scores in the active site of 3WJS.

Docking – Siddha herbal- MV Kashayam- HIV- anti retroviral drugs

"To ELUCIDATE THE ROLE OF METABOLITES PRESENT IN SIDDHA HERBAL PREPARATION M V KASHAYAM IN PREVENTING THE ENTRY AND MULTIPLICATION OF HIV ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 2, page no.a59-a65, February-2022, Available :http://www.jetir.org/papers/JETIR2202008.pdf

"To ELUCIDATE THE ROLE OF METABOLITES PRESENT IN SIDDHA HERBAL PREPARATION M V KASHAYAM IN PREVENTING THE ENTRY AND MULTIPLICATION OF HIV ", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 2, page no. ppa59-a65, February-2022, Available at : http://www.jetir.org/papers/JETIR2202008.pdf