• Irfan Ahmad Paray
• Brajesh Pathak

With an aim to formulate and evaluate sustained release floating microspheres of Esomeprazole, it was observed that these remain buoyant in the stomach for prolonged period of time and these are used as multiunit dosage form and drug release optimization and show efficiency level. Thereby with hydrophilic polymers the GI retention can be enhanced and reduce frequency of dosing, thereby minimizing the occurrence of side effects, site specificity, increase the effectiveness of the drug and better patient compliance Hence it is concluded that sustained release floating microspheres of Esomeprazole may provide a convenient dosage form for achieving best performance and release and show good bioavailability.

Floating Microspheres, Esomeprazole, Sustain release

"Formulation and Evaluation of Floating Microsphere of Esomeprazole", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 2, page no.b544-b557, February-2022, Available :http://www.jetir.org/papers/JETIR2202164.pdf

"Formulation and Evaluation of Floating Microsphere of Esomeprazole", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 2, page no. ppb544-b557, February-2022, Available at : http://www.jetir.org/papers/JETIR2202164.pdf