• Manishkumar Jinabhai Tank
• Navinkumar Arjanbhai Kucha
• Dhanji Rajani
• G. M. Malik

Various substituted acetophenone were reacted with 2,4-dintro phenyl hydrazine subjected to Vilsmeier- Haack reaction yielded pyrazole-4-carbaldehyde derivatives (2a-j). A series of Schiff base and Azetidine were synthesized by reaction of 6-methyl-N-(4-pyridin-3-yl)-pyrimidin-2-yl)-benzene-1,3-diamine with various pyrazole-4- carbaldehyde derivatives (2a-j) in order to determine their in vitro antimicrobial and antifungal activities against clinically isolated strains. The chemical structures were confirmed by FTIR, 1H-NMR, 13C and LCMS.

pyrazole-4-carbaldehyde derivatives, Schiff base, Azetidine, 6-methyl-N-(4-pyridin-3-yl)-pyrimidin-2-yl)-benzene-1,3-diamine

"Synthesis, characterization and biological characteristics of Pyrimidine derivatives of Schiff base and Azetidine", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 2, page no.c216-c223, February-2022, Available :http://www.jetir.org/papers/JETIR2202247.pdf

"Synthesis, characterization and biological characteristics of Pyrimidine derivatives of Schiff base and Azetidine", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 2, page no. ppc216-c223, February-2022, Available at : http://www.jetir.org/papers/JETIR2202247.pdf