• Dr.Sandeep Bajpai
• Dr.Madhu Tripathi

Fluoride is a persistent bioaccumulator, which keeps on accumulating in visceral organs through environment. Thus even low concentration can cause harmful consequences to aquatic organisms chronically exposed to it, particularly fish due to their poor ability to metabolize and eliminate xenobiotics as compared to other higher vertebrates. The toxicity of fluoride to freshwater catfish, Heteropneustes fossilis, a common edible fish of India was evaluated after chronic exposure to sublethal concentration 77.20 mg F/L (one-fifth of 96 hour LC50 value) for a period of three months. Alterations in biochemical constituents such as total protein and lipid were estimated in different tissues such as gill, liver and kidney of the exposed fish and observations were made after 45 and 90 days. The levels of both the biomolecules was found to be decreased significantly in comparison to control after both the durations. The results indicate that fluoride is capable to alter biomolecules in fishes causing great loss in their growth and nutritive value. Such fish when consumed as food lead to the accumulation of toxicant in the soft tissues of human body and can promote ‘fluorosis’ which is a crippling disease.

Fluoride toxicity, Protein, Lipid, Soft tissues, Heteropneustes fossilis

"Sublethal Effects of Fluoride on some Biochemical Profiles of Freshwater Stinging Catfish, Heteropneustes fossilis (Bloch)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 2, page no.c344-c354, February-2022, Available :http://www.jetir.org/papers/JETIR2202262.pdf

"Sublethal Effects of Fluoride on some Biochemical Profiles of Freshwater Stinging Catfish, Heteropneustes fossilis (Bloch)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 2, page no. ppc344-c354, February-2022, Available at : http://www.jetir.org/papers/JETIR2202262.pdf