• neetu pandey
• pooja
• sanjay devli

ABSTRACT: Metformin is an orally Anti Diabetic drug, which is available in various brands in local markets in Dehradun. The main purpose of this study is to compare and evaluate different brand of Metformin HCL tablets 500mg with Diabecon DS Himalaya. In this study we selected four different brand of Metformin Hydrochloride tablet 500mg and Diabecon DS Himalaya tablets from local market in Dehradun and evaluated various quality control parameters (physical and chemical parameters) as per official methods for comparison. Weight variation for all four different brands of metformin hydrochloride tablets within ±5% of their average weight and when friability test was performed we found that the friability was not more than 1%, all the metformin hydrochloride tablet disintegrate within 15 minutes, percentage release of all brands of metformin hydrochloride tablets was found not less than 75% according IP specification limit within 45 minutes. Same procedure followed for Diabecon DS Himalaya tablets.

: Metformin Hydrochloride, Diabecon DS Himalaya, Dissolution, Quality control parameters

"COMPARATIVE EVALUATION OF DIFFERENT BRANDS OF METFORMIN HCL TABLETS 500mg WITH DIABECON DS HIMALAYA TABLETS 500mg", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 2, page no.d721-d723, March-2022, Available :http://www.jetir.org/papers/JETIR2202392.pdf

"COMPARATIVE EVALUATION OF DIFFERENT BRANDS OF METFORMIN HCL TABLETS 500mg WITH DIABECON DS HIMALAYA TABLETS 500mg", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 2, page no. ppd721-d723, March-2022, Available at : http://www.jetir.org/papers/JETIR2202392.pdf