• Rudrangshu chatterjee
• Swati tripathi
• ML Aggarwal
• Ajit Varma

Medicinal plants and probiotics both have potential antimicrobial activity against antibiotic-resistant pathogens which causes gastrointestinal diseases in human. Multi drug resistance is a big issue in medical field and these multi drug resistance enteric pathogenic bacteria generally found in sewage water. The microorganisms have developed resistance to many commercial antibiotics due to the various uses of antibacterial drugs. This study involved isolation, identification and molecular characterization of multidrug resistance Salmonella strains from sewage water treatment plants located in Delhi. Main aim of this study was to identify anti-microbial efficacy of Murraya koenigii, Piper betle, Tagetes erecta and Aegle marmelos leaves extract and their combination of with Lactobacillus plantarum which is commonly used probiotic against gastrointestinal disorder. Combination of Murraya koenigii leaf extract and Lactobacillus plantarum has shown effective against both Salmonella strains isolated from sewage water in the study. This combination has shown significant results as compared to rest of three plant leaf extract used for the study. Thus combination therapy may be effective for treatment of gastrointestinal diseases and could be suggest as an alternative medicine.

Salmonella, Murraya koenigii, Piper betle, Tagetes erecta, Aegle marmelos, Lactobacillus plantarum

"Comparative Study Of Medicinal Plant Extracts and Probiotic Against Multidrug Resistance Salmonella Isolates", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 3, page no.b632-b643, March-2022, Available :http://www.jetir.org/papers/JETIR2203181.pdf

"Comparative Study Of Medicinal Plant Extracts and Probiotic Against Multidrug Resistance Salmonella Isolates", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 3, page no. ppb632-b643, March-2022, Available at : http://www.jetir.org/papers/JETIR2203181.pdf