• ASHA KUMARI
• Puja Kumari Jaiswal

The Ageratum genus belongs to the Asteraceae family. It is a medicinal herb that has traditionally to be used to treat dysentery and diarrhea in many traditional cultures. It's also a nematicide and a pesticide. The aim of this study was to investigate genotoxic effects of aqueous extracts (10,20,30,40 & 50) from Ageratum conyzoides leaf and flower extracts on Allium cepa root tip. For this purpose, Allium cepa onion bulbs were treated with the Ageratum conyzoides leaf and flower extracts for 24 h. The root tips from each bulb were excised and fixed in Carney’s fixative for 24 hours. Mitotic preparation was made by hydrolysing the root tips in a mixture of 1 N HCL and 2 % acetocarmine (1:9), at 60+2C for 2 hrs. The result of this study showed that aqueous extracts reduced mitotic index, but induced chromosomal aberrations and mitotic aberrations in comparison with control. Aqueous extracts induced disturbed metaphase, precocious movement, unorientation, laggard, stickiness, fragments, bridges, late separation, etc. furthermore, these effects were related to extract concentrations. These results showed that Ageratum conyzoides aqueous extracts have mitotic and genotoxic effects.

Vicia faba L., plant extract, genotoxic effect, Allium cepa L.

"Mitotic Effects and Genotoxicity Effects of Leaf and Flower Extracts of Ageratum conyzoides on Allium cepa.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 3, page no.f177-f186, March-2022, Available :http://www.jetir.org/papers/JETIR2203520.pdf

"Mitotic Effects and Genotoxicity Effects of Leaf and Flower Extracts of Ageratum conyzoides on Allium cepa.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 3, page no. ppf177-f186, March-2022, Available at : http://www.jetir.org/papers/JETIR2203520.pdf