• Talakkootr. Jose Jaison
• Pasupuleti. Prameela
• Penmatsa. Sai Lakshmi Venkata Navya
• Vadlamudi. Sharon Roja
• Balla. NagalakshmiBalla. Nagalakshmi

A rapid and stability-indicating ultra-performance liquid chromatography method was developed for quantification of Avelumab,, Trifluridine, Daunorubicin, Axitinib to get some more advantages over other methods already developed in different methods we can single method. The method was developed according to ICH and to develop the calibration curve for all drugs using this method. In this method a simple isocratic conditions of mobile phase comprising water and Acetonitrile in a ratio of 20:80, v/v at a flow rate of 0.5 mL/minute over waters x bridge C18, 50 × 4.6 mm, 3.5μm column at room temperature was maintained. The method showed excellent linear response with correlation coefficient (R2) values of 0.999 for Avelumab,, Trifluridine, Daunorubicin, Axitinib which was within the limit of correlation coefficient.

UPLC, Avelumab, Trifluridine, Daunorubicin, Axitinib.

"ESTIMATION OF FOUR DIFFERENT ONCOLOGY DRUGS USING ADVANCED LIQUID CHROMATOGRAPHY TECHNIQUE (UPLC)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 4, page no.g232-g239, April-2022, Available :http://www.jetir.org/papers/JETIR2204635.pdf

"ESTIMATION OF FOUR DIFFERENT ONCOLOGY DRUGS USING ADVANCED LIQUID CHROMATOGRAPHY TECHNIQUE (UPLC)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 4, page no. ppg232-g239, April-2022, Available at : http://www.jetir.org/papers/JETIR2204635.pdf