UGC Approved Journal no 63975

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 9 Issue 4
April-2022
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2204635


Registration ID:
400968

Page Number

g232-g239

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Title

ESTIMATION OF FOUR DIFFERENT ONCOLOGY DRUGS USING ADVANCED LIQUID CHROMATOGRAPHY TECHNIQUE (UPLC)

Abstract

A rapid and stability-indicating ultra-performance liquid chromatography method was developed for quantification of Avelumab,, Trifluridine, Daunorubicin, Axitinib to get some more advantages over other methods already developed in different methods we can single method. The method was developed according to ICH and to develop the calibration curve for all drugs using this method. In this method a simple isocratic conditions of mobile phase comprising water and Acetonitrile in a ratio of 20:80, v/v at a flow rate of 0.5 mL/minute over waters x bridge C18, 50 × 4.6 mm, 3.5μm column at room temperature was maintained. The method showed excellent linear response with correlation coefficient (R2) values of 0.999 for Avelumab,, Trifluridine, Daunorubicin, Axitinib which was within the limit of correlation coefficient.

Key Words

UPLC, Avelumab, Trifluridine, Daunorubicin, Axitinib.

Cite This Article

"ESTIMATION OF FOUR DIFFERENT ONCOLOGY DRUGS USING ADVANCED LIQUID CHROMATOGRAPHY TECHNIQUE (UPLC)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 4, page no.g232-g239, April-2022, Available :http://www.jetir.org/papers/JETIR2204635.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"ESTIMATION OF FOUR DIFFERENT ONCOLOGY DRUGS USING ADVANCED LIQUID CHROMATOGRAPHY TECHNIQUE (UPLC)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 4, page no. ppg232-g239, April-2022, Available at : http://www.jetir.org/papers/JETIR2204635.pdf

Publication Details

Published Paper ID: JETIR2204635
Registration ID: 400968
Published In: Volume 9 | Issue 4 | Year April-2022
DOI (Digital Object Identifier):
Page No: g232-g239
Country: Vijayawada, Krishna District, Andhra Pradesh, India .
Area: Chemistry
ISSN Number: 2349-5162
Publisher: IJ Publication


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