• Sachin Kumar
• Nikita Rawat
• Shrestha Sarkar
• Vikash Kumar
• Chinmay Goyel, Rajan Kushwaha

For systemic drug delivery, the buccal route is desirable because it bypasses the hepatic first pass metabolism and delivers a high bioavailability of the medication to the systemic circulation. A number of disorders can be better treated with buccal bioadhesive films, which release topical medications into the mouth over time at a controlled release rate. According to this article, recent advances in buccal adhesive delivery systems will be reviewed in order to give young scientists a solid foundation for avoiding the pitfalls of formulation design. Some drugs are metabolised in the liver before reaching the intestines, therefore buccal drug delivery may be an option to oral administration. The buccal mucosa has long been considered an appropriate location for giving drugs since it is painless and may be quickly and easily removed if the therapy has to be ended or interrupted. An optimal mucoadhesive system, the advantages and disadvantages of buccal delivery, the factors that affect buccal absorption and various types of patches, as well as their manufacturing process and composition, were all discussed in this overview of buccal. drug delivery systems.

Buccal drug delivery system, Buccal patches, Mucoadhesive, Mechanism of buccal mucosa, Composition of the buccal patch, Evaluation of buccal patch.

"PATCH AND FILM BASE ORAL DRUG ADMINISTRATION: NEW METHODS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 5, page no.b817-b833, May-2022, Available :http://www.jetir.org/papers/JETIR2205210.pdf

"PATCH AND FILM BASE ORAL DRUG ADMINISTRATION: NEW METHODS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 5, page no. ppb817-b833, May-2022, Available at : http://www.jetir.org/papers/JETIR2205210.pdf