• RASIKA D. BHALKE
• MAHENDRA A GIRI
• Yash S. Lodha
• Nikita N. Shirsath
• Surabhi A. Sicchi

Alzheimer's disease (AD) first described by German psychiatrist Alois Alzheimer in 1906, is a disorder and is the main cause of dementia which causes degeneration of the cells in the brain and is characterized by a decline in thinking. Two main causes for AD were postulated viz. cholinergic and amyloid. In addition to these increasing age,, head injuries, genetic factors, infections, vascular diseases, and environmental factors are considered as progressive factors of AD. For the treatment of AD cholinesterase enzyme inhibitors and N-methyl d-aspartate (NMDA) antagonists are used to get symptomatic relief, but no curative treatment is available for AD. Herbal medicine has long been widely used to enhance the treatment of symptoms of dementia and improve cognitive impairment in East Asian countries. The review summarises pathophysiology of AD and usefulness of medicinal plants in the treatment of AD.

Alzheimer's disease, pathophysiology of AD, herbal treatments

"A COMPREHENSIVE REVIEW ON THE HERBS USED FOR TREATMENT OF ALZHEIMER’S DISEASE (AD)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 5, page no.f463-f480, May-2022, Available :http://www.jetir.org/papers/JETIR2205666.pdf

"A COMPREHENSIVE REVIEW ON THE HERBS USED FOR TREATMENT OF ALZHEIMER’S DISEASE (AD)", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 5, page no. ppf463-f480, May-2022, Available at : http://www.jetir.org/papers/JETIR2205666.pdf