• G. Sindu Sravanthi
• Syed.Sadik
• Ch. Ramya
• M. Tejaswe
• N. Hema latha

The objective of the present study was to develop Phenytoin sodium Fast dissolving tablets to improve the versatility, patient counselling and accurate dosing. The FDT’s are prepared by direct compression method using different concentrations of superdisintegrants. A combination of Crosspovidone & Crosscarmellose sodium is used as superdisintegrants. The prepared tablets are evaluated for pre-compression & Post compression parameters. A total of nine formulations are prepared with varied concentrations of superdisintegrants and they are compared with marketed product Dilantin tablets and the results showed that formulation F5 was found to be the best among the all 9 Phenytoin sodium FDT’s as it exhibited faster disintegration time when compared to other formulations & showed a drug release of 99.25% drug release at the end of 60mins.

superdisintegrants, phenytoin sodium, fast dissolving tablets,

"formulation and evaluation of phenytoin sodium fast dissolving tablets by direct compression method using various super disintegrants", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 6, page no.c703-c715, June-2022, Available :http://www.jetir.org/papers/JETIR2206287.pdf

"formulation and evaluation of phenytoin sodium fast dissolving tablets by direct compression method using various super disintegrants", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 6, page no. ppc703-c715, June-2022, Available at : http://www.jetir.org/papers/JETIR2206287.pdf