• Shinde Tejasvee Ramchandra
• Dattaprasad N. Vikhe
• Ravindra S. Jadhav

Abstract: Nonsteroidal anti-inflammatory drugs (NSAIDs) produce their therapeutic activities through inhibition of cyclooxygenase (COX), the enzyme that makes prostaglandins (PGs). They share, to a greater or lesser degree, the same side effects, including gastric and renal toxicity. Recent research has shown that there are at least two COX isoenzymes. Effective therapies for peptic ulcers use alternatives that control acidic hypersecretion and its direct effects on the gastric mucosa. The two main classes of drugs used to treat acid-related disorders include proton pump inhibitors (PPI) that inhibit the hydrogen pump in the parietal cell directly, independently of any membrane receptor stimulation, and histamine type 2 receptor antagonists (H2RAs). To evaluate the anti-inflammatory & anti-ulcer activity of drugs there are many in-vivo & in-vitro methods that can be use.

Antiinflammatory Antiulcer

"Invivo & Invitro evaluation techniques for Anti-inflammatory and Anti-Ulcer drugs.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 6, page no.h106-h118, June-2022, Available :http://www.jetir.org/papers/JETIR2206715.pdf

"Invivo & Invitro evaluation techniques for Anti-inflammatory and Anti-Ulcer drugs.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 6, page no. pph106-h118, June-2022, Available at : http://www.jetir.org/papers/JETIR2206715.pdf