UGC Approved Journal no 63975(19)

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Published in:

Volume 9 Issue 7
July-2022
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2207366


Registration ID:
405941

Page Number

d506-d520

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Title

SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION, DFT-STUDIES, MOLECULAR DOCKING, DNA BINDING ABILITY, MTTASSY AND ANTIMICROBIAL ACTIVITY OF NEW COPPER(II) COMPLEX WITH IMINODIACETIC ACID AND NEOCUPROINE

Abstract

[Cu(neocuproine)(Imino)](NO3)2 is a new copper (II) complex that was synthesised and characterised using elemental analysis, IR, EPR and UV-visible. A square-pyramidal (4+1) Cu(NO3)2 coordination sphere is visible in the complex. UV-Vis, DFT investigations, molecular docking, fluorescence, TGA, cyclic voltammetry, viscometric methods, and MTT assy were used to evaluate the current complex's binding relationship with calf thymus DNA (CT DNA) and propose a partial intercalation binding mode. The compound was discovered to have substantial cytotoxic effects against a human cell type (HepG2) as well as antibacterial and antifungal properties.

Key Words

Copper (II) complex; Iminodiacetic acid; neocuproine; Cytotoxicity; DNA binding , MTT assy, DFT, and docking.

Cite This Article

"SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION, DFT-STUDIES, MOLECULAR DOCKING, DNA BINDING ABILITY, MTTASSY AND ANTIMICROBIAL ACTIVITY OF NEW COPPER(II) COMPLEX WITH IMINODIACETIC ACID AND NEOCUPROINE", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 7, page no.d506-d520, July-2022, Available :http://www.jetir.org/papers/JETIR2207366.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION, DFT-STUDIES, MOLECULAR DOCKING, DNA BINDING ABILITY, MTTASSY AND ANTIMICROBIAL ACTIVITY OF NEW COPPER(II) COMPLEX WITH IMINODIACETIC ACID AND NEOCUPROINE", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 7, page no. ppd506-d520, July-2022, Available at : http://www.jetir.org/papers/JETIR2207366.pdf

Publication Details

Published Paper ID: JETIR2207366
Registration ID: 405941
Published In: Volume 9 | Issue 7 | Year July-2022
DOI (Digital Object Identifier): http://doi.one/10.1729/Journal.30973
Page No: d506-d520
Country: VILLUPURAM, TAMIL NADU, India .
Area: Chemistry
ISSN Number: 2349-5162
Publisher: IJ Publication


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