• Chukka Ajay Kumar
• B.Aksa
• A.Pushpalatha
• Md. Khadeer Hussain
• N.Surendra

In this study novel Pyridopyrimidine derivatives were designed. Designed derivative compounds against 3PBL molecular docking stimulation was carried out with MCULE and insilico ADMET prediction procedures. The results of docking study revealed that the binding profile for designed compounds PPD-III-FPB.HCl and PPD-IV-FPB.HCl was found significant interactions with 3PBL when compared with Paliperidone. The further scope of synthesized derivatives of novel Pyridopyrimidine derivatives need to evaluation of various in vivo pharmacological Studies to bring potentially active molecules.

Pyridopyrimidine, ADMET prediction, PPD-III-FPB.HCl, PPD-IV-FPB.HCl, MCULE, 3PBL, Paliperidone.

"MOLECULAR DOCKING AND ADMET STUDIED OF NOVEL PYRIDOPYRIMIDINE DERIVATIVES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 7, page no.d632-d638, July-2022, Available :http://www.jetir.org/papers/JETIR2207382.pdf

"MOLECULAR DOCKING AND ADMET STUDIED OF NOVEL PYRIDOPYRIMIDINE DERIVATIVES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 7, page no. ppd632-d638, July-2022, Available at : http://www.jetir.org/papers/JETIR2207382.pdf