• P. P. Pathare
• Dr. S. E. Bhandarkar
• Prof. B. P. Khobragade

The Schiff bases ligand has been found extensive use in the field of research and field of interest. The term Schiff base is normally applied to these compounds when they are being used as ligands to form coordination complexes with metal ions. Such complexes occur naturally, for instance in corrin, but the majority of Schiff bases are artificial and are used to form many important catalysts. Schiff bases are azomethine (-C=N-) linked compounds that are typically formed by the condensation of carbonyl compounds (aldehydes/ketones) with primary aliphatic / aromatic / hetroaromatic amines. Schiff bases are known for their antitumor, antifungal, antiviral, antibacterial and anticancer activities. The intermolecular hydrogen bonding ability and proton transfer equilibrium of Schiff bases offer them excellent bioactivity. The Schiff base complexes of transition metal have played prominent role in the developments of coordination chemistry. Insecticides, pesticides, bactericides, and fungicides have been developed using metal complexes derived from Schiff bases. Transition metal complexes of Schiff base ligands are a very interesting topic for young scientists to study because of the variety of possible structures for the ligand depending on the ketones/amines used and their specific industrial or biological applications. The present work focuses on comparative study of various Schiff base metal complexes based on its biological applications with the help of available research work.

Schiff Bases, Metal Complexes, Biological Applications, Review

"A Comparative Study of Schiff Base Metal Complexes Based on Its Biological Application: A Review", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 7, page no.f49-f56, July-2022, Available :http://www.jetir.org/papers/JETIR2207507.pdf

"A Comparative Study of Schiff Base Metal Complexes Based on Its Biological Application: A Review", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 7, page no. ppf49-f56, July-2022, Available at : http://www.jetir.org/papers/JETIR2207507.pdf