UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 9 Issue 7
July-2022
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2207520


Registration ID:
406001

Page Number

f149-f157

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Title

COMPARATIVE STUDY OF TAB. NIFEDIPINE VERSUS TAB. LABETALOL IN HYPERSENSETIVE DISORDER OF PREGNANCY

Abstract

Hypertension in pregnancy is the important cause of mortality and mortality in not only mother but also in fetus. The incidences of hypertensive disorders ranges from 2.8% of all pregnancies and contributes to 9% of maternal mortality in Asia and 12% in India 3,4 the Gestational hypertension is diagnosed when the BP exceeds 140/90 in the absence of protein urea or pathological edema. One hundred pregnant women having blood pressure ≥ 160/110 mmHg were selected and divided in two groups. The Group A treated with oral Tab. Nifedipine 10 mg and the Group B treated with oral Tab. Labetalol 100 mg. The most common complaints were pain in abdomen, epigastric pain, severe headache, visual disturbances. The most common age group was 21 to 25 years in group A (62%0 and group B(64%) (p= 0.949) and mean age group A and group B was 22.00 ± 2.53 years and 22.34 ± 2.58 years ( p= 0.507) respectively. Majority of the women in group A (80%) and group (62%) had primi para (p =0.076). The most common complaint was pain in abdomen 94% in group A vs 92% in group B (p = 0.500). It was observed that, 96% of the women in group B had onset of the blood pressure control within 30 minutes where as 94% of the women achieved the target blood pressure within 31 to 60 minutes( p< 0.001). The mean duration for the onset of blood pressure control was also significantly low in the group B compared to group A ( 29.40 ± 6.75 vs 52.80 ± 12.94 and p < 0.001) . The onset of blood pressure control in most of the women with group A (94%) and group B (86%) was achieved with two doses ( p = 0.093) and mean number of doses required in group A and group B (2.08 0.34 vs1.96 0.46) was also comparable ( p = 0.136) Interpretation and conclusion is Tab. Nifedipine requires significant shorter duration for the onset of blood pressure control compared to Tab. Labetalol without additional doses.

Key Words

Nifedipine, labetalol, hypertension

Cite This Article

"COMPARATIVE STUDY OF TAB. NIFEDIPINE VERSUS TAB. LABETALOL IN HYPERSENSETIVE DISORDER OF PREGNANCY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 7, page no.f149-f157, July-2022, Available :http://www.jetir.org/papers/JETIR2207520.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"COMPARATIVE STUDY OF TAB. NIFEDIPINE VERSUS TAB. LABETALOL IN HYPERSENSETIVE DISORDER OF PREGNANCY", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 7, page no. ppf149-f157, July-2022, Available at : http://www.jetir.org/papers/JETIR2207520.pdf

Publication Details

Published Paper ID: JETIR2207520
Registration ID: 406001
Published In: Volume 9 | Issue 7 | Year July-2022
DOI (Digital Object Identifier):
Page No: f149-f157
Country: -, -, India .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication


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