• Shanmugam Rajalakshmi
• Venkatesan Vinayagam
• Mahadevimangalam Narayanasamy Arumugham

Abstract: The formation of new copper(II) [Cu(4-Amino)2(Ace)NO3]NO3 and [Cu(4-Amino)2(Acry)NO3]NO3 have been synthesized and characterized by elemental analysis, UV-Vis, FT-IR spectrum analyses were used to describe the ligands, which were 4-Aminobenzoic Acid with Acetanilide and Acrylamide. Viscosity testing, cyclic voltammetry, and electronic absorption spectroscopy were used to examine the complexes' interactions with CT-DNA. The complexes with CT-DNA were studied to determine their intrinsic binding constants (Kb), which revealed that they are modest groove binders. Additionally, the electronic structure of produced ligands and their complexes was studied computationally using a density functional theory (DFT) calculation. Staphylococcus, E.coli and Pseudomonas antibacterial testing Trichoderma Viride and Clodosorium were used as test organisms for the complex's antifungal properties.

Keywords: Acetanilide, Acrylamide, DNA binding, Density Functional Theory and Antimicrobial activity.

"Synthesis, Characterization, DNA Binding-Studies, Density Functional Theory and Antimicrobial Activity of Copper(II) Complexes with 4-Aminobenzoic Acid and Acetanilide, Acrylamide", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 7, page no.g366-g374, July-2022, Available :http://www.jetir.org/papers/JETIR2207653.pdf

"Synthesis, Characterization, DNA Binding-Studies, Density Functional Theory and Antimicrobial Activity of Copper(II) Complexes with 4-Aminobenzoic Acid and Acetanilide, Acrylamide", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 7, page no. ppg366-g374, July-2022, Available at : http://www.jetir.org/papers/JETIR2207653.pdf