• Anitha Sadhula
• Apoorva S

Increasing demand for the novel drugs to combat multiple ailments and resistance to several existing drugs lead to discovery or development of new entities. In the same contest coumarins the natural occurring heterocyclic compound showing variety of biological activities including antifungal activity, antioxidants, enzyme inhibitors, growth regulators, antithrombotic, anticoagulant, antimicrobial, hepatoprotective etc. This coumarin is studied with conjugation of other heterocyclic compound called imidazole, a five membered ring system containing two nitrogen's, at one and three position. It is chosen for conjugation as it has several advantages like is to synthesise, naturally occurring, compound fewer side effects, chemically active with variety of biological actions including gastrointestinal disorders, hypersensitivity, antibacterial, anticancer, antitubercular, antifungal, analgesic. Anti-HIV, antiarrhythmics, convulsions, migraine, etc. so this review is an overview of how the conjugated system will help in combating various problems of resistance and elicit pharmacological actions. Here is complete review on chemistry and pharmacological actions of coumarin and imidazole molecules and their conjugated system which shows several biological activities. This review also contains several synthetic strategies produced in several research papers listed with the scheme.

Coumarin, imidazole, coumarin linked imidazoles, synthesis, biological activity

"A REVIEW ON SYNTHETIC STRATEGIES AND BIOLOGICAL ACTIVITIES OF COUMARIN LINKED IMIDAZOLE DERIVATIVES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 8, page no.a124-a130, August-2022, Available :http://www.jetir.org/papers/JETIR2208017.pdf

"A REVIEW ON SYNTHETIC STRATEGIES AND BIOLOGICAL ACTIVITIES OF COUMARIN LINKED IMIDAZOLE DERIVATIVES", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 8, page no. ppa124-a130, August-2022, Available at : http://www.jetir.org/papers/JETIR2208017.pdf