• Amartya De
• Susanta Kumar Bandyopadhyay
• T.K. Mandal
• M.C.Banerjee

This study was conducted to evaluate the effect of Bauhinia acuminata (BA) stem bark against sodium arsenite (NaAsO2) induced toxicosis in adult albino rats. Forty eight (48) adult albino rats having body weight 150-200 gm of either sex were randomly divided into four groups (A0, A1, A2 and A3) each containing twelve. Sodium arsenite was administered at 4mg/kg daily in drinking water for 90 days to all rats of group A1, A2 and A3. The rats of group A2 was orally treated with stem bark extract of BA (1/10th of LD50) at 300mg/kg daily from 91 day to 120 day whilst stem bark extract of BA (1/20th of LD50) at 150 mg/kg daily orally was administered in group A3 from 91 day to 120 day. Only water was given to rats of group A0 and considered as control. Blood samples were collected at different days for analysis of haemogram, biochemical parameters like ALT, AST, BUN, CRT. Tissue samples were collected to study activity of SOD, MDA, GSH and catalase. Histopathology of some vital organs also conducted after completion of experiment. The results reveal that stem bark extraction of Bauhinia acuminata may be effective to reduce the toxic effect of arsenic.

Arsenic, rats, Bauhinia acuminata, Histopathology, Antioxidant activity, Biochemical parameters, Haemogram.

"Ameliorative Effects of Bauhinia acuminata stem bark extract against chronic arsenicosis in rats", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 8, page no.b296-b321, August-2022, Available :http://www.jetir.org/papers/JETIR2208139.pdf

"Ameliorative Effects of Bauhinia acuminata stem bark extract against chronic arsenicosis in rats", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 8, page no. ppb296-b321, August-2022, Available at : http://www.jetir.org/papers/JETIR2208139.pdf