UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 9 Issue 10
October-2022
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2210216


Registration ID:
503537

Page Number

c144-c151

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Title

Exploration of Anti-microbial activity of copacīnī (Smilax china) root on various pathogens causing Urinary Tract Infection – an In vitro study

Abstract

Introduction The present study was carried out with an objective to investigate the antimicrobial potentials of various extracts of copacīnī (Smilax china) fruits on common uropathogen strains. Material and Methods Aqueous, ethanol, chloroform, petroleum ether extracts of Smilax china L. were evaluated for potential antimicrobial activity against certain uropathogen strains. The antimicrobial activity was determined in the extracts using agar well diffusion method. The antibacterial activities of extracts (5%, 10% and 15% w/v) of Smilax china were tested against Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis, Klebsiella pneumonia and Enterococcus faecalis. Zone of inhibition of extracts were compared with that of standard drug Azithromycin 1 % w/v(Positive control) and DMSO(Negative control) for antibacterial activity. Observations and results As compared with standard drug, the results revealed that all extracts possesses anti bacterial activity but ethanol extract was found to have maximum activity against all pathogens taken in this study. Maximum antibacterial activity was reported against Proteus mirabilism by all extracts. The phytochemical analyses of the plants were also carried out which was found to be similar to standard values of API. Conclusion In vitro findings of this study confirmed urobactericidal activity of Smilax china on common uropathogens.

Key Words

Smilax china, in vitro antimicrobial activity, UTI, uropathogens, in vitro study

Cite This Article

"Exploration of Anti-microbial activity of copacīnī (Smilax china) root on various pathogens causing Urinary Tract Infection – an In vitro study", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 10, page no.c144-c151, October-2022, Available :http://www.jetir.org/papers/JETIR2210216.pdf

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2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Exploration of Anti-microbial activity of copacīnī (Smilax china) root on various pathogens causing Urinary Tract Infection – an In vitro study", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 10, page no. ppc144-c151, October-2022, Available at : http://www.jetir.org/papers/JETIR2210216.pdf

Publication Details

Published Paper ID: JETIR2210216
Registration ID: 503537
Published In: Volume 9 | Issue 10 | Year October-2022
DOI (Digital Object Identifier):
Page No: c144-c151
Country: -, -, India .
Area: Engineering
ISSN Number: 2349-5162
Publisher: IJ Publication


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