• Varad Kolapkar
• Govind Lagad
• Ganesh Kute
• Prof.Ankita Bankhele
• Dr. Rajesh Oswal

To improve dissolution of poorly water-soluble drugs and thus enhancing their bioavailability, the dispersion of one or more active pharmaceutical ingredients in a carrier at solid state is used. This process is known as solid dispersion. It has engrossed significant interest as an efficient meal of improving the dissolution rate. It happens due to dispersion of poorly water- soluble drugs with water-soluble carriers. The one of the most challenging aspects in formulation development is solubility behavior of drugs. The number of poor water soluble as radically increase. Compare to conventional formulations such as tablets on capsule, solid dispersion prepared by various methods can be used which have many benefits over the above conventional dosage form. For the preparation of solid dispersion, few of the aspects are to be considered such as; selection of carrier and methods of physicochemical characterization. In this review, an emphasis is put on solubility, various types of solid dispersion, BCS classification, carriers, solid dispersion techniques, mechanism to enhanced dissolution in solid dispersion, characterization, advantages, disadvantages and the applications of the solid dispersion.

Solid dispersion, BCS classification, solubility behaviour

"An Overview on Solid Dispersions", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 11, page no.c489-c505, November-2022, Available :http://www.jetir.org/papers/JETIR2211254.pdf

"An Overview on Solid Dispersions", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 11, page no. ppc489-c505, November-2022, Available at : http://www.jetir.org/papers/JETIR2211254.pdf