• Atikha Aprilia Harahap
• M. Fidel G. Siregar
• Makmur Sitepu
• Henry S. Siregar
• Sarma N. Lumbanraja

Abstract Background : It is known that during menopause process, estrogen levels fall, triggering variety of pathological conditions such as vitamin D deficiency. Vitamin D has been shown to play a role in lipid metabolism, therefore its deficiency causes a more atherogenic lipid profile. Aim: This study aims to determine the correlation between vitamin D3 levels and lipid profiles in postmenopausal patients. Methods : This study is an observational analytic study with a cross-sectional research design conducted at the Universitas Sumatera Utara Hospital starting from July 2022 until the number of samples is met. The examination results of vitamin D3 levels and lipid profiles were obtained from laboratory examinations by taking blood samples. If data is normally distributed, then data is analyzed using Pearson Correlation Test. If data is not normally distributed, then data is analyzed using Spearman Correlation Test.. Results : Based on Pearson correlation test, it was found that there was a significant correlation between vitamin D3 levels and total cholesterol (p = 0.002), LDL (p = 0.007), and triglycerides (p = 0.000) levels but not significant with HDL (p = 0.074). Analysis with Chi-Square test showed that there was a significant relationship between vitamin D3 levels and cholesterol levels (p = 0.036), LDL levels (p = 0.033) and triglyceride levels (p = 0.036) but also not significant with HDL (p = 0.159) levels. Conclusion: In postmenopausal patients, vitamin D3 levels had a significant relationship with lipid profiles that included total cholesterol, LDL, and triglyceride levels but did not have a significant relationship with HDL levels.

Keywords: Menopause, Vitamin D3, total cholesterol, LDL, LDL, triglycerides

"Correlation of Vitamin D3 Levels and Lipid Profiles in Menopausal Patients", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.9, Issue 12, page no.e442-e450, December-2022, Available :http://www.jetir.org/papers/JETIR2212461.pdf

"Correlation of Vitamin D3 Levels and Lipid Profiles in Menopausal Patients", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.9, Issue 12, page no. ppe442-e450, December-2022, Available at : http://www.jetir.org/papers/JETIR2212461.pdf