UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 10 Issue 1
January-2023
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2301069


Registration ID:
506806

Page Number

a535-a543

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Title

Antimicrobial, antioxidant and cytotoxic activities of hemolymph from marine spiny lobster, Panulirus homarus (Linnaeus, 1878) from Vizhinjam coast, Kerala.

Abstract

P. homarus is a marine spiny lobster which is edible and widely cultivated species in Asian countries. Antimicrobial activity of haemolymph collected from; P. homarus (PHH) were tested against clinical pathogens. Antimicrobial activities of PHH were carried out by well diffusion method. PHH exhibit a significant activity E.coli, S. aureus, S.typhi, S.pyogenes and P.chrysogenum. Results were compared with standard antibiotic drugs Gentamycin and Clotrimazole. The antioxidant potential of the PHH was measured by 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay. After DPPH activity of PHH at different concentrations (1.56-1000µg) it exhibited antioxidant activity with IC50 value of 172.53. Cytotoxic activity at different concentrations (0.25-100 mg/mL) was tested against MCF-7 cell line by MTT assay. PHH exhibited potential cytotoxicity against these cell lines after 24 hours in a dose dependent manner. These findings indicate that PHH may be used in clinical applications.

Key Words

Marine lobster, P. homarus, antimicrobial activity, well diffusion method, DPPH radical scavenging assay, MTT assay, cytotoxic assay.

Cite This Article

"Antimicrobial, antioxidant and cytotoxic activities of hemolymph from marine spiny lobster, Panulirus homarus (Linnaeus, 1878) from Vizhinjam coast, Kerala.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 1, page no.a535-a543, January-2023, Available :http://www.jetir.org/papers/JETIR2301069.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Antimicrobial, antioxidant and cytotoxic activities of hemolymph from marine spiny lobster, Panulirus homarus (Linnaeus, 1878) from Vizhinjam coast, Kerala.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 1, page no. ppa535-a543, January-2023, Available at : http://www.jetir.org/papers/JETIR2301069.pdf

Publication Details

Published Paper ID: JETIR2301069
Registration ID: 506806
Published In: Volume 10 | Issue 1 | Year January-2023
DOI (Digital Object Identifier):
Page No: a535-a543
Country: Cuddalore, Tamilnadu, India .
Area: Biological Science
ISSN Number: 2349-5162
Publisher: IJ Publication


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