• Hemlata D Hire
• Kunal S Surwade
• Dipti G Phadtare

A gel is a semi-solid formulation having an external solvent phase which is either apolar (organogels) or polar (hydrogels) that is immobilized inside the voids contained in a three-dimensional networked structure. Organogels are bi-continuous systems composed of gelators and apolar solvents that may or may not contain water molecules entrapped inside the self-assembled structures of the gelators. When used at a concentration of around 15%, the gelators may undergo physical or chemical interactions, resulting in the formation of self-assembled fibrous structures that become entangled with one another, resulting in the formation of a three-dimensional networked structure. The resulting three-dimensional networked structure blocks the flow of the external apolar phase. Sterol, sorbitan monostearate, lecithin, and cholesteryl anthraquinone derivatives are examples of gelators. The unique characteristics such as thermo-reversibility, viscoelasticity, and versatility impart a longer shelf-life and ease of preparation to organogels. These characteristics can easily be adjusted by simple formulation modifications, resulting in highly-structured architectures. The organogels have ability to entrap both hydrophilic and hydrophobic compounds within its structure have also widened the scope of use of organogels in various delivery systems. These characteristics make these structures excellent matrices with the ability to deliver an efficient drug concentration over a long period of time, thus enhancing the chances for patient compliance. Their hybridization with other materials also allows for customizing their potential as drug delivery systems. Organogels have potential applicability in numerous ways; hence this article discusses the various aspects of it.

Organogels, Organogelators, Drug delivery

"A REVIEW ON ORGANOGELS: AS A NEW FORMULATION", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 1, page no.e233-e248, January-2023, Available :http://www.jetir.org/papers/JETIR2301439.pdf

"A REVIEW ON ORGANOGELS: AS A NEW FORMULATION", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 1, page no. ppe233-e248, January-2023, Available at : http://www.jetir.org/papers/JETIR2301439.pdf