• Dr.MASTAN VALI SHAIK
• Dr.M.S DASTAGEER

Schiff base complexes have attracted wide attention due to their important role in analytical chemistry, organic synthesis, metallurgy, refining of metals, electroplating and photography. It has been proved that azomethine linkage (C=N) of Schiff base provides the opportunity for the stupendous biological activities such as antitumor, antibacterial, antifungal and herbicidal activities. In the present study Schiff bases of Carboxymethyl Chitosan and cinnamaldehyde Schiff bases were prepared and characterized by FTIR, XRD, TGA and DSC studies. The results show the formation of Schiff bases with the amine of carboxymethyl chitosan and cinnamaldehyde. The Iron (II), Cobalt(II) and Zinc (II) metal complexes were prepared by sol gel method. The complexes were again characterized by FTIR, XRD, TGA and DSC studies. The antioxidant activity of the complexes was studied by DPPH studies. The cytotoxicity of the complexes towards HeLa cell lines was also studied. From the results it can be concluded that the complexes are less toxic and have good antioxidant activity. The results are discussed.

Antioxidant, Carboxymethyl Chitosan, Cytotoxic studies, cinnamaldehyde, Iron, Cobalt, Zinc schiff bases.

"Synthesis, Spectroscopic Studies and Biological Activities of Iron (II), Cobalt (II) and Zinc (II) Schiff Base Complexes", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 1, page no.e622-e643, January-2023, Available :http://www.jetir.org/papers/JETIR2301485.pdf

"Synthesis, Spectroscopic Studies and Biological Activities of Iron (II), Cobalt (II) and Zinc (II) Schiff Base Complexes", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 1, page no. ppe622-e643, January-2023, Available at : http://www.jetir.org/papers/JETIR2301485.pdf