• Vijay Arjun Bagul
• Dr. Sushama Raju Ambadekar
• Anand Radheshyam Tiwari
• Jayesh Pandharinath Tamhanekar

A new simple, specific, linear, precise, accurate and robust UV Spectroscopic method was developed for the determination of Clonidine Hydrochloride in tablet dosage form. Solution was scanned over UV-visible range for its wavelength of maximum absorbance. The wavelength of maximum absorbance for Clonidine Hydrochloride was found to be 271 nm. The method was validated as per ICH guidelines. Linearity range was observed in concentration of 40.02 – 120.06 μg/mL for Clonidine Hydrochloride. The mean percentage recovery of Clonidine Hydrochloride was found to be 99.1%. The correlation coefficient was close to 1. Developed method was found to be robust for the intended use. A simple, precise and cost-effective UV spectroscopic method is very beneficial for routine analysis in pharmaceutical industry.

Clonidine Hydrochloride, UV Spectroscopy, Validation

"Development and Validation of Simple and Rapid UV Spectroscopic Method for estimation of Clonidine Hydrochloride in Tablet Dosage Form", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 3, page no.b152-b164, March-2023, Available :http://www.jetir.org/papers/JETIR2303118.pdf

"Development and Validation of Simple and Rapid UV Spectroscopic Method for estimation of Clonidine Hydrochloride in Tablet Dosage Form", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 3, page no. ppb152-b164, March-2023, Available at : http://www.jetir.org/papers/JETIR2303118.pdf