• Professor Dr. Khaleda Islam
• Md. Ruhul Amin
• Ummy salma Munni

Abstract This experimental study was conducted to determine the efficacy of B12 intervention of peripheral neuropathy patients. A pretested, semi-structured standard questionnaire and randomized sampling technique was used to collect the data, the number of calculated sample size was 93, and SPSS version 20.0 was used for data analysis. This study period was 1.5 years duration from 1st July 2021 to 31st December 2022. Study found that average age of the respondents was 51.75 9.68 years among them 44.10% of the respondents were male and 55.90% were female. Study found that average food consumption scores 144.29 33.26. Nutritional status of the respondents’ 10.80% were normal weight, 54.80% were overweight and 34.40% were obese with their average BMI 27.64 3.85. Study revealed that food consumption score of the respondents was good and there were no underweight patients found in this study. It was observed that 89.20% of the respondents were suffering from motor disorders, 66.70% were autonomic disorders, and most of the respondents complained sensory disorders. Study found that average serum vitamin B12 level before treatment 387.78 79.47 pmol/L and after treatment 828.24 72.78 pmol/L, whereas average pain score before treatment 8.31 1.07 and after treatment 2.81 1.79 and it was measure by Visual Analogue Scale. There was a statistically significant effect on peripheral neuropathy patient after B12 intervention (t-value=9.68 and p value=0.000) and it was measure by serum B12 level.

Peripheral Neuropathy, B12 Intervention, , Body Mass Index, Total Food Score, Dietary Diversity, Somatic and Autonomic symptoms

"Vitamin B12 mediated therapeutic interventions in patients with cyanocobalamin (vitamin B12) deficient peripheral neuropathy", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 3, page no.c71-c80, March-2023, Available :http://www.jetir.org/papers/JETIR2303211.pdf

"Vitamin B12 mediated therapeutic interventions in patients with cyanocobalamin (vitamin B12) deficient peripheral neuropathy", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 3, page no. ppc71-c80, March-2023, Available at : http://www.jetir.org/papers/JETIR2303211.pdf