• Harshavardhan Sagar

The current study was conducted to synthesize new azo-dyes and to study their chemical structures in details. Methods: A new azo compounds is prepared by (E)-5-((2-fluorophenyl)diazenyl)-2-hydroxybenzaldehyde with Ethyl 4-aminobenzoate to form ethyl 4-(((Z)-5-((E)-(2-fluorophenyl)diazenyl)-2-hydroxybenzylidene)amino)benzoate. The azo ligand was identified by Mass, 1H-NMR, UV-Vis. and IR spectra, in addition to elemental analysis measurement. Analytical data revealed that all the complexes exhibited 1:2 metal–ligand ratios. On the basis of magnetic susceptibility measurements, suitable geometry was proposed for each complex. IR spectra of complexes showed that the ligand is coordinated to the metal ions in bidentate manner with oxygen and nitrogen donor sites of hydroxy azo and azo nitrogen. These findings suggested octahedral geometry for all complexes. Also, biological evaluation of all synthesized compound showed moderate to good activity against employed strains. All the comp The synthesized derivatives were screened for their in-vitro antibacterial activity against three gram-positive bacterium, Enterococcus fecalis (E. fecalis), Staphylococcus aureus (S. aureus) and Bacillus subtilis (B. Subtilis) and two gram-negative bacteria Klebsiella pneumonia (K. pneumoniae) and Pseudomonas aeruginosa (P. aeruginos) strains using streptomycin as standard references. In-vitro antifungal activity was screened against four fungal strains Aspergillus Niger (A. Niger) and Aspergillus flavus (A. flavus) using Fluconazole as standard references. The ligands and Schiff bases exhibited significant activity toward both Gram-positive, Gram-negative bacterial and fungal strains. Further, all the Complexes were stable, non-ionic and exhibited octahedral geometry around the metal centre.

"Preparation and Spectral characterization of new chelate complexes derived from Azo Ethyl 4-Aminobenzoate ligand", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 3, page no.g229-g236, March-2023, Available :http://www.jetir.org/papers/JETIR2303634.pdf

"Preparation and Spectral characterization of new chelate complexes derived from Azo Ethyl 4-Aminobenzoate ligand", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 3, page no. ppg229-g236, March-2023, Available at : http://www.jetir.org/papers/JETIR2303634.pdf