UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 10 Issue 4
April-2023
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2304C02


Registration ID:
514069

Page Number

m5-m26

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Title

Pitching Edge of Cellular and Molecular Process of Kynurenine Pathway in Neuronal and Non-Neuronal Conditions

Abstract

Tryptophan has several metabolic pathways, about 95% of tryptophan involves in the kynurenine pathway. Organs including the brain, liver, and immune cells are involved in this pathway. Many substances of biological importance are formed on the kynurenine pathway which involves kynurenine, quinolinic acid, kynurenic acid and anthranilic acid. In recent years, this pathway has received attention in the scientific community due to its involvement in neurotoxic, neuroprotective, anti-inflammatory, antidiabetic, anti-cancer, Huntington's disease, seizures, cardiovascular disease, osteoporosis, and immune properties. An imbalance of this pathway causes immune system activation and the production of different compounds such as neurotoxic compounds, which makes the kynurenine pathway a promising target for therapeutic intervention. This review aims to correlate migraine, Parkinson’s disease, Alzheimer’s disease, Inflammation, Rheumatoid arthritis, and Acute and chronic kidney diseases with the Kynunerine pathway.

Key Words

Tryptophan, Kynurenine pathway, Kynurenic acid, Quinolinic acid.

Cite This Article

"Pitching Edge of Cellular and Molecular Process of Kynurenine Pathway in Neuronal and Non-Neuronal Conditions", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 4, page no.m5-m26, April-2023, Available :http://www.jetir.org/papers/JETIR2304C02.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"Pitching Edge of Cellular and Molecular Process of Kynurenine Pathway in Neuronal and Non-Neuronal Conditions", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 4, page no. ppm5-m26, April-2023, Available at : http://www.jetir.org/papers/JETIR2304C02.pdf

Publication Details

Published Paper ID: JETIR2304C02
Registration ID: 514069
Published In: Volume 10 | Issue 4 | Year April-2023
DOI (Digital Object Identifier):
Page No: m5-m26
Country: Erode, Tamil Nadu, India .
Area: Pharmacy
ISSN Number: 2349-5162
Publisher: IJ Publication


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