• Dr.G.KIRAN
• V.VENKATESULU
• B.HEMAVATHI
• B.JAYA PRAKASH REDDY
• P.SRAVANI

The present study is aimed to evaluate the anxiolytic activity of ethanol and aqueous extract of HELIANTHUS ANNUS using elevated plus maze test (epm) model in rats. ethanol and aqueous extract of HELIANTHUS ANNUS had increased number of entries and time spent in open arms while they decreased the number of entries and duration of time spent in closed arm of the EPM. In a similar fashion, the diazepam increased the percentage of time spent and percentage of arm entries in the open arms (*P <0.05, **P <0.01). the bark had anxiolytic activity (*P <0.05, **P <0.01) in EPM.

HELIANTHUS ANNUS ,Anxiolytic activity, Elevated plus maze test etc.

"THE CURRENT STUDY AIMED AT INVESTIGATION OF EFFECTIVENESS OF ETHANOLIC AND AQUEOUS EXTRACT OF HELIANTHUS ANNUS IN ANXIOLYTIC DISESE IN EXPERIMENAL ABLINO RATS USING ELEVATED PLUS MAZE APPARATUS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 5, page no.e18-e29, May-2023, Available :http://www.jetir.org/papers/JETIR2305403.pdf

"THE CURRENT STUDY AIMED AT INVESTIGATION OF EFFECTIVENESS OF ETHANOLIC AND AQUEOUS EXTRACT OF HELIANTHUS ANNUS IN ANXIOLYTIC DISESE IN EXPERIMENAL ABLINO RATS USING ELEVATED PLUS MAZE APPARATUS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 5, page no. ppe18-e29, May-2023, Available at : http://www.jetir.org/papers/JETIR2305403.pdf