• Rajeev Rattan

Clematis species have been a source of various traditionally useful and pharmacologically effects. The plants are prominently climbers and woody vines. The species are mosly wild. The species Clematis argentilucida, Clematis montana, Clematis grata, and Clematis ganpiniana were selected to study on their traditional use, chemical composition and pharmacological effects reported in literature. In folklore these species are used as for the treatment of wound, rheumatism, arthralgia, aphonia hoarseness, limb numbness, migraine, nervous disorders, skin infections, liver complications, hypertension and diabetes. The triterpenoid saponins are the dominant compounds of these species. However, flavonoids, alkaloids, lignans, coumarins, steroids and volatile oils have also been reported. The chemical constituents isolated were hederagenin aglycone based new saponins- 1 from Clematis argentilucida, 1 from Clematis montana, 1 from Clematis grata, and 3 from Clematis ganpiniana and 6 oleanane aglycone based saponins from Clematis montana. The pharmacological activities have been antioxidant, cytotoxic, antimicrobial, antidiabetic, hepatoprotectve, and anti-inflammatory activities. As such these species has emerged as good source of traditional medicines, chemical diversity and pharmacological effects. Though the isolated compounds from these species have been reported for their pharmacological effects but uncharacterized crude extracts were employed in most of the activities. Such species need to be explored scientifically for their bioactive principle and exploited as potential drug. The review will help the researchers to select medicinally potential species of Clematis for future research.

Clematis argentilucida, Clematis montana, Clematis grata, Clematis ganpiniana

"PHYTOCHEMICALS AND PHARMACOLOGICAL EFFECTS OF CLEMATIS SPECIES-A REPORT", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 5, page no.k200-k207, May-2023, Available :http://www.jetir.org/papers/JETIR2305A25.pdf

"PHYTOCHEMICALS AND PHARMACOLOGICAL EFFECTS OF CLEMATIS SPECIES-A REPORT", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 5, page no. ppk200-k207, May-2023, Available at : http://www.jetir.org/papers/JETIR2305A25.pdf