• Amreen Master
• Azima Madha
• Nazhat Malek
• Samir Madhi
• Het Mahida

Ginger herb is grown in many areas around the world it is used as medicinal herb. However, only a limited amount of research exists to support their efficacy. The aim of the present work is to demonstrate the antispasmodic effect of ginger (Zingiber officinale) on chicken intestine in vitro. the chicken ileum Segments 2 cm long are cut mounted in a 10 ml tissue automatic organ bath containing Ringer lock solution at 37°C and aerated with oxygen, where One end of the ileum was attached to an S-shaped aeration tube and the other end to an isotonic frontal writing lever attached to Sherrington recording drum with kymograph. The tissue was allowed to equilibrate for 30 min under an optimum load. The results revealed that the effect of low doses of ginger on exogenous acetyl choline (ACh) and Histamine induced contraction is Antispasmodic as a dose of 0.4ml=40µg of ginger / tissue bath produced decrease in the magnitude of ach induced contraction, while doses of 0.4 ml = 40µg of ginger/of tissue bath produced decrease in magnitude of Histamine induced contraction.

Spasm, Spasmogenic, Spasmolytic, Acetylcholine, Contraction, Charley horse, Gingerol, Twitching, Distension, Downstream Signalling, Antagonism.

"TO STUDY THE EFFECT OF VARIOUS SPASMOGENIC & SPASMOLYTIC DRUGS & VARIOUS GINGER EXTRACTS ON CHICKEN ILEUM.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 5, page no.l625-l633, May-2023, Available :http://www.jetir.org/papers/JETIR2305B86.pdf

"TO STUDY THE EFFECT OF VARIOUS SPASMOGENIC & SPASMOLYTIC DRUGS & VARIOUS GINGER EXTRACTS ON CHICKEN ILEUM.", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 5, page no. ppl625-l633, May-2023, Available at : http://www.jetir.org/papers/JETIR2305B86.pdf