UGC Approved Journal no 63975(19)

ISSN: 2349-5162 | ESTD Year : 2014
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Published in:

Volume 10 Issue 5
May-2023
eISSN: 2349-5162

UGC and ISSN approved 7.95 impact factor UGC Approved Journal no 63975

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Published Paper ID:
JETIR2305D39


Registration ID:
517759

Page Number

n229-n257

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Title

SOLUBILITY ENHANCEMENT OF ROSUVASTATIN CALCIUM USING SOLVENT EVAPORATION TECHNIQUE

Abstract

Preparation of Rosuvastatin Calcium by Using HPMC Polymers and Solid Dispersion Method, Rosuvastatin calcium is a Dyslipidemic agent, which act as a selective competitive inhibitor of HMG CoA educates enzyme and is used in the treatment of hyperlipidemia. In the present work, Solid Dispersion was prepared by solvent evaporation method to increase the solubility of Rosuvastatin Calcium. Solid dispersions were evaluated by determining percentage yield, in vitro dissolution profile. The prepared solid dispersion is formulated into Tablet dosage form and characterized by various parameters i.e., weight variation, Friability, Hardness, and dissolution. The evaluated parameters of Tablet dosage form increase in solubility and dissolution rate of the pure drug.

Key Words

Solvent evaporation technique, Rosuvastatin, Bioavailability, Polymer-HPMC

Cite This Article

"SOLUBILITY ENHANCEMENT OF ROSUVASTATIN CALCIUM USING SOLVENT EVAPORATION TECHNIQUE", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 5, page no.n229-n257, May-2023, Available :http://www.jetir.org/papers/JETIR2305D39.pdf

ISSN


2349-5162 | Impact Factor 7.95 Calculate by Google Scholar

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 7.95 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Cite This Article

"SOLUBILITY ENHANCEMENT OF ROSUVASTATIN CALCIUM USING SOLVENT EVAPORATION TECHNIQUE", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 5, page no. ppn229-n257, May-2023, Available at : http://www.jetir.org/papers/JETIR2305D39.pdf

Publication Details

Published Paper ID: JETIR2305D39
Registration ID: 517759
Published In: Volume 10 | Issue 5 | Year May-2023
DOI (Digital Object Identifier):
Page No: n229-n257
Country: Bharuch, Gujarat, Gujarat, India .
Area: Pharmacy
ISSN Number: 2349-5162
Publisher: IJ Publication


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