• Chandani Kushwaha
• Dr. Yogita Tyagi
• Ms. Hiba Parveen
• Praveen Kumar Ashok

Rosacea is a chronic, recurrent condition that can present as a number of different cutaneous symptoms. The centrofacial inflammatory dermatosis condition has serious financial, physical, and psychological effects. There are numerous topical, oral, and systemic therapies available. However, rosacea therapy is still challenging. It is difficult for both patients and clinicians because to the complex character of the disease and the lack of a thorough grasp of the pathogenesis. Recently, three clinical trials have provided evidence for the effectiveness of topical ivermectin cream in treating rosacea. Ivermectin exhibits a broad-spectrum anti-parasitic action, specifically targeting Demodex mites residing in the pilosebaceous units of individuals with papulopustular rosacea. The application of ivermectin cream successfully eradicates these mites. Ivermectin reduces cellular and humoral immune responses and has anti-inflammatory properties as well. The formation of inflammatory lesions in rosacea appears to be mostly influenced by inflammatory processes. Additionally, there is some proof that it exhibits antimicrobial efficacy against Chlamydia trachomatis and Myobacterium tuberculosis. According to recent clinical research on rosacea, ivermectin reduced the number of inflammatory lesions more effectively than a vehicle and had excellent tolerability. Ivermectin exhibits antibacterial, antiparasitic, anti-inflammatory, and antimicrobial properties. This article offers a thorough analysis of papulopustular rosacea treatment options, including the newly popular usage of 1% ivermectin cream. Topical 1% cream has emerged as a unique treatment for papulopustular rosacea. Although ivermectin 1% is a clinically effective drug, poor adherence remains a concern owing to topical use. Finally, the agent has the potential to be a useful medicine when used alone or in combination with other agents.

Papulopustular, Phymatous, Demox mite, Erythematotelangiectatic

"A systematic review on role of Ivermectin in Rosacea", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 5, page no.p164-p169, May-2023, Available :http://www.jetir.org/papers/JETIR2305G24.pdf

"A systematic review on role of Ivermectin in Rosacea", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 5, page no. ppp164-p169, May-2023, Available at : http://www.jetir.org/papers/JETIR2305G24.pdf