• BANDARU CHENCHURATHNAIAH
• VASURU KESAVULU
• ASUPATHRI USHA RANI

Arsenic intoxication disturbs Haemotological system and Biochemical parameters indicating its toxicity towards the blood and hematopoietic system is one of the important sources of ROS generation and initiates cytotoxicity. The Wistar rats were divided into 4 groups, having 6 rats in each group. Group I is treated as control, Group II received Sodium arsenite (8 mg/kg BW) for 15 days, Group III received Sodium arsenite (8 mg/kg BW) for 30 days and Group IV received Sodium arsenite (8 mg/kg BW) for 45 days. The present study results on haematological parameters showed significant decrease in RBC, WBC, Lymphocytes, Haemoglobin, Platelets and RBC indices – PCV, MCV, MCH and MCHC with a significant increase in Neutrophils, Monocytes, Basophils and Eosinophils and administration of arsenic to rats was associated with increase in Blood glucose, Triglycerides, Total cholesterol, VLDL and LDL with decline in Total proteins, Serum albumin and HDL. These results indicate a characteristic effect of arsenic in the alterations of Hematological and Biochemical parameters.

Arsenic; Biochemical; Hematological; and Wistar rats

"STUDY OF HEMATOLOGICAL AND BIOCHEMICAL ALTERATIONS IN SODIUM ARSENITE EXPOSED WISTAR ALBINO RATS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org), ISSN:2349-5162, Vol.10, Issue 6, page no.i733-i741, June-2023, Available :http://www.jetir.org/papers/JETIR2306880.pdf

"STUDY OF HEMATOLOGICAL AND BIOCHEMICAL ALTERATIONS IN SODIUM ARSENITE EXPOSED WISTAR ALBINO RATS", International Journal of Emerging Technologies and Innovative Research (www.jetir.org | UGC and issn Approved), ISSN:2349-5162, Vol.10, Issue 6, page no. ppi733-i741, June-2023, Available at : http://www.jetir.org/papers/JETIR2306880.pdf